This article was last updated by on

10 Best Herbicides For Plants [2023 Updated]

The moment your flower and vegetable plants are about to flourish, uninvited guests, i.e., weeds, bother your plants and obstruct their growth. Use the best herbicides to help your desired plants in such cases.

Herbicides are the chemical component to inhibit unwanted plants from competing with your main crop for food, light and space. Depending on the weeds in your garden, you can use pre-emergence, post-emergence, selective, or non-selective herbicides.

Before deciding on one, let’s learn in detail about the composition, use, and advantage of a few best herbicides for your plants.

Types of Herbicides For Specific Plants

You might be wondering why weed inhibitors are called herbicides.

Actually, weeds are any greens that grow out of the place. It means grass, herbs or any plant hampering the activity of the main plant, so the chemical against them is popularly called ‘herbicides’.

Generally, herbicides are categorized based on the mode and time of application and how they work on the weed.

Mode of application

  • Contact: These herbicides work by directly contacting the leaves and stem of the target plant, causing them to wither and die. They are often used to spot-treat individual plants.
  • Systemic: Mostly used to control deep-rooted perennial weeds. The plant absorbs herbicides and transports them throughout, including the roots.

Time of Application

  • Pre-emergence: Applied before weeds emerge from the soil after planting the main crop. Used in lawn care to prevent the growth of weeds like crabgrass.
  • Post-emergence: Incorporated in the soil after the weed seedling appears
  • Pre-plant: Mixed in the soil before even sowing the plants

Based on Specificity

  • Selective Herbicides: Target specific weeds, either broad-leaf, grass or sedge, while leaving others unharmed, Popular in agriculture
  • Non-selective Herbicides: Unlike the above, the non-selective ones restrict the growth or kill all the green in contact with the chemical, including your grown plants.

Factors to Consider When Choosing Herbicides

Before anything, you must consider the type of weeds you are working with when choosing the best herbicides for your plants.

Also, the plants grown in your garden, like marigolds, cosmos flowers, and jasmine, each have different weeds bothering them.

Weeds may be either broad-leaf, grass, or sedge, categorically differing in lifecycle. Simultaneously, their treatment differs.

Similarly, the formulation of herbicides and their active ingredients vary per their target weeds. The active ingredient in a herbicide is the component that kills the weeds.

Look below for the factors you need to consider.

  • Correctly recognize the target weed.
  • Identify the life cycle of the problematic weeds, whether annual, biennial, or perennial, to choose the best herbicide.
  • Looks out for the active ingredients effective against the specific weed you want to kill or suppress.
  • Know the weed’s garden history to check whether they are herbicide resistant.
  • Check the soil type and pH as it affects the crop injury potential of the herbicides and the residual effect on the subsequent crop.
  • Compare the cost of different herbicides with the same ingredient to make it cost-effective.

Pro Tip: Follow the manufacturer’s instructions carefully to ensure safe and effective use.

10 Best Herbicides On the Market

Scrolling down the internet, you’ll find herbicides in various packages and forms, like liquids, and granules, including some organic options.

But considering the factors like active ingredients, price point, use, and longevity, here we have listed a few best herbicides for your plants.

Best for Large AreasRM43 Weed Killer
Best Along Fences and DrivewayGordon’s SpeedZone Lawn Weed Killer
Best Non-Toxic HerbicideGreen Gobbler Vinegar Weed Killer
Best Weed Killer ConcentrateSunday Weed Warrior
Best OverallSpectracide Weed & Grass Killer
Best for LawnSouthern Ag Amine 2,4-D
Best Weed Killer for LawnRoundup For Lawn
Best for Grass WeedOrthro Weed B Gon
Best Pre-EmergentPreen Weed Preventer Plus Plant Food
Best Selective HerbicideTenacity Turf Herbicides

1. RM43 Weed Killer 

If you are looking for a herbicide to clear your entire backyard, RM43 Weed Killer is the one for you. 

Not just the sideways, but a single gallon of RM43 can treat the 43,243 square feet area of your choice.

These glyphosate and imazapyr-based herbicides can kill and prevent entire vegetation and are equally effective for spot control.

Likewise, they efficiently act upon weeds, vines, shrubs, crabgrass, purslane, and oxalis, making them one of the best overall plant herbicides.

Further, the herbicide is rainproof after 2 hours and keeps your garden weed assured for as long as a year after application.


  • Easy to use
  • Long-lasting
  • Cost-effective


  • Lacks immediate result
  • Non-selective

2. Gordon’s SpeedZone Lawn Weed Killer

Apart from the garden, if weeds invade your entire fence, use Gordon’s Lawn Killer, a combination of 2,4-D, dicamba acid, and carfentrazone-ethyl.

Basically, you apply this product to a recently mowed lawn during dry days as it can easily wash away by rain.

The result is visible within a few hours of application.

A photo of Gordon’s SpeedZone Lawn Weed Killer
Gordon’s SpeedZone Lawn Weed Killer


  • Targets broad-spectrum weeds
  • Effective weed control


  • Extremely toxic to pets 
  • Temperature sensitive 

3. Green Gobbler Vinegar Weed Killer

The Green Gobbler have developed a glyphosate-free herbicide option that saves you from all the toxic effect of harsh chemical. 

Regardless of its eco-friendly compositions, it completely desiccates weeds and grasses like white clover, moss, nutsedge, dandelions, and many more in less than 24 hours of application.

Moreover, this organic formula is 20% stronger than regular vinegar spray.

If the product fails to give the best result or doesn’t meet your expectations, the 30-day money-back policy saves you.


  • Free from toxic chemicals
  • It doesn’t require dilution


  • Requires frequent application

4. Sunday Weed Warrior

Sunday Weed Warrior follows the organic thread, which helps you bid goodbye to pesky weeds, thistle, algae, moss, and crabgrass within 20 minutes or less.

You only lightly shake the bottle, check the nozzle, and spray.

Once these ammoniated soapy herbicides dry away, your pet can roam around.
A photo of Sunday Weed Warrior herbicides
Sunday Weed Warrior

Moreover, the formulation is non-staining and can be used in flower beds, near the patio, and along the sidewalk. 


  • Non-corrosive
  • Fast-acting composition
  • More efficacious on grass weeds


  • Non-selective may hamper desired plants.

5. Spectracide Weed & Grass Killer

Spectracide is a non-selective formula for maintaining the golf course, sports stadium, and turf grass. 

As for home garden and agriculture use, these highly effective herbicides work on the roots of broad-leaf weeds like ivy, geranium, milkweed, plantain, etc.

Usually, it comes in a 64-ounce container that needs to be diluted. But you can also get them in a ready-to-use spray.

Since Spectricide comes concentrated and rainfast after 15 min of application, you might have to keep your pets and kids away from the site and the bottle.


  • Kills the root
  • Quick and effective
  • Budget-friendly


  • Wipes out all the vegetation that comes in contact
  • Requires dilution and spray bottle

6. Southern Ag Amine 2,4-D

The undiluted formula of Southern Ag Amine 2,4-D is one of the best broad-leafs targeting herbicides. 

To use it, dilute a tablespoon of concentrate into a gallon of water and spray over the weeds like clover, dandelions, and crabgrass.

Meanwhile, you may see the results as early as 30 minutes, but on average, it takes three days to desiccate the weeds fully.


  • Works on major Broad-leaf weed
  • Value for money


  • Not resistant to rain
  • Extremely toxic to pets
  • It needs to be diluted

7. Roundup For Lawn

As the name suggests, the Roundup for Lawn is a read-to-use weed killer specifically for your lawn.

Besides glyphosate, pelargonic acid works deep into the root of over 250 weeds, including Northern grasses like Kentucky bluegrass, bermudagrass, and zoysiagrass. 

A photo of Roundup for Lawns1
Roundup for Lawns


  • Ready to spray
  • Kills summer weeds and Northern grasses
  • Immediate action and rainproof after 3 hours


  • Presence of toxic chemical
  • It may cause skin irritation

8. Orthro Weed B Gon

Orthro Weeds B Gon is a selective herbicide that protects your lawn, especially flower beds, from invasive weeds.

Although under budget, the product becomes wash-proof after an hour of application and gives good results against crabgrass, clover, and Northern grasses like fescue and ryegrass.

It is recommended to spray the product only below the temperature of 90°F  to avoid drift towards desired plants.

Moreover, a 16-ounce bottle, once diluted, can easily treat 3,200 square feet.


  • Comparatively cheaper
  • Targets tough weeds


  • Requires separate sprayer
  • Not pet-friendly
  • Temperature sensitive

9. Preen Weed Preventer Plus Plant Food

Unlike the others on this list, Preen Garden Weed Preventer is a granular formulation that helps prevent weeds from popping up in your garden, supplying food for your desired plants.

But, the chemical is not rainproof and doesn’t work in pre-emerged weeds.

A photo of Preen Weed Preventer.
Preen Weed Preventer Plus Plant Food

However, the flip-top applicator aids in the easy application of the herbicides.


  • Easy to spread 
  • It can be applied any time of the year
  • Safe to use around vegetables and bulb crop


  • Cannot control already-grown weeds

10. Tenacity Turf Herbicides

Next on the list is Tenacity Turf Herbicides, a selective herbicide with quick results and 4.4 ratings on Amazon.

You can use it as a pre-emergence herbicide on turfgrass or simply as post-emergent on barnyard grass, foxtails, goosegrass, and many more.
The product’s active ingredient, mesotrione, refrains the target weed’s photosynthesis and thus controls its growth.


  • Longer shelf life
  • Dual use, both as pre-emergent and post-emergent


  • Slightly on the expensive end
  • Mixing and measuring hassle

From Editorial Team 

Most herbicides contain toxic chemicals and ingredients, so avoid health hazards using protective masks and glasses.

Also, please keep the product away from your pet and kid’s reach, safeguarding them from any mishaps.